USP 797 is a standard for sterility that pharmaceutical compounding and preparation facilities must demonstrate. USP 797 is set by the United States Pharmacopeia and National Formulary (USP-NF) and ensures patient safety by protecting pharmaceuticals from contamination during preparation. Following USP 797 reduces infection, contamination, and improper dosage to maintain superior quality products in facilities such as pharmacies, operating rooms, chemotherapy units, hospital pharmacies, and nuclear pharmacies.
Meeting USP 797 Environmental Quality & Control Requirements
Meeting USP 797 standards is critical to the safety of pharmacy environments, as it ensures clean and sterile conditions for compounding and preparing pharmaceutical products. Sterile compounding pharmacy environments and other cleanrooms can demonstrate compliance by following USP 797 standards for monitoring and controlling airborne particles. It is necessary to follow USP 797 to comply with FDA and local regulations, protect against liability, and remain competitive.
USP 797 provides guidelines for the following:
ACPH. Hazardous drug (HD) storage rooms require at least 12 air changes per hour (ACPH) for refrigerated, sterile, and nonsterile storage. Buffer rooms and anterooms with access to HDs require 30 ACPH, and anterooms without HD access require 20 ACPH. Buffer rooms with a redundant HEPA filtration system require 12 ACPH.
Temperature. Cleanroom temperatures are dependent on the comfort of personnel. It can change relative to the necessary gowning or personal protective equipment (PPE). Sweat and shivering result in more particulate shedding by personnel, so temperatures must not be too low or too high. Uncomfortable temperatures can also encourage staff to shed gowning to cool down or wear unauthorized clothing for warmth.
Humidity. Clean rooms must maintain an adequate humidity level to prevent personnel from sweating due to high humidity and static buildup in low humidity. Low humidity can also cause residual adhesives from labels to stick to surfaces like gloves. According to USP 797, relative humidity (RH) must be below 60% at all times.
Pressure. Non-HD compounding pharmacies must maintain positive air pressure to keep airborne particulates, contaminants, and dirt from entering through doors, crevices, and ceiling tiles from outside the cleanroom. HD compounding pharmacies require a negative pressure buffer and positive pressure anteroom to prevent contamination and control HD particles.
Air quality. Maintaining quality standards requires monitoring of airborne particles. Viable particles require monitoring every week, and non-viable particles require monitoring every six months.
Why Your Central HVAC System Won’t Help You Meet USP 797
Sterile compounding pharmacies within confined spaces often become a hotspot when using a standard building air conditioner that cannot keep up with the humidity. Relying on a standard HVAC system can often times result in a space above USP 797 humidity requirements. Maintaining USP 797 compliance requires an HVAC system designed for pharmaceutical applications. Air Innovations offers HVAC solutions to maintain USP 797 compliance.
Air Innovations HVAC Solutions
The HEPAir® Cleanroom HVAC Unit by Air Innovations is the ideal solution to maintaining USP 797 humidity, temperature, pressure, and air quality standards for sterile compounding pharmacies. The HEPAir unit operates independently of the building HVAC system, only serving isolation areas such as cleanrooms, pharmacies, and laboratories. Facilities can also implement several HEPAir units to provide additional air quality and climate control where necessary.
Contact Us for Environmental Control Solutions for Your Compounding Facility
Maintaining USP 797 requirements in your sterile compounding pharmacy space is crucial in delivering a safe product. Rely on Air Innovations’ HEPAir Cleanroom HVAC Unit to ensure USP 797 compliance. As a leader in designing and manufacturing environmental control solutions, we have the necessary knowledge and experience to deliver quality systems to help you abide by critical industry standards. For more information about our HEPAir Cleanroom HVAC Unit or other environmental control solutions, contact us today.
Indoor climate control is a wonder of modern engineering, but it can be extremely expensive and wasteful. Nearly 13% of the United State’s energy consumption comes from heating and cooling buildings. Instead of controlling the climate of entire buildings, a better solution may be to control the climate of individual spaces in buildings. Installing a personal climate control system at individual office desks puts each worker in control of their environment while helping businesses save energy and money on utility bills.
Personalized climate control systems in office buildings reduce the amount of heated or cooled air that needs to be supplied throughout the building because only certain areas need cooling at any given time. Cooling vents automatically switch off when a worker leaves their desk, eliminating unnecessary energy consumption. Studies show that providing temperature controls for individual desks can help cut down energy costs by half.
Benefits of Personal Climate Control Systems
Implementing personal climate control systems into workspaces provides a range of benefits to the company and to its employees. Some of the benefits include the following:
Enhanced Energy Efficiency and Reduced Costs
Energy consumption and its costs are a matter of concern for businesses. Personal ventilation systems can help cut costs by enhancing energy efficiency.
Improves Workforce Productivity
The comfort of workers is one of the major factors that improve productivity. People who work for long hours need solutions that enhance comfort. A personal climate control system allows personnel to customize their environment to their comfort level, thereby improving productivity.
Limits Air Borne Diseases Transmission
One of the major causes of the spread of airborne diseases is central HVAC systems. HVAC systems circulate the air throughout the premises, carrying with germs and bacteria with it which results in the spread of various airborne diseases. It has become critically important to limit this spread within facilities given today’s global health situation, and a personal climate control system can be an effective solution.
Nearly 60% of complaints regarding office environment are related to temperature. In any office space, there are diverse people of different sizes and gender with varying climate preferences. There is no perfect temperature to fit the needs of all of them. Providing workers with personal climate control makes it possible to optimize the workspace environment according to individual needs.
MyZone® System is an innovative personal climate control solution that caters to the personal comfort of individual workers. This revolutionary personal climate control device is attached to the surfaces in personal workspaces, integrating lighting control, environmental control, and lift functions within a single unit. It comes with a non-fixed controller, which means you can position it anywhere on your desk without a problem. The MyZone system has a variety of features and benefits:
Non-fixed user controller for user convenience
Highly energy-efficient design
Automatic integrated motion sensor for additional power savings. Following 10 minutes of inactivity, the system shuts off automatically.
Variable options for cooling and heating
Adjustable louvers allow you to direct air towards yourself
Programmable for up to 15 users
Integrated sit/stand desk leg lift control
Adjustable generator for white noise
Adjustable calendar and clock
Task light dimmer
Option of HEPA Filtration
Effectiveness of HEPA Office vs Desk Filtration
Along with climate control, MyZone® personal climate control system with optional HEPA filtration can also improve the air quality and provide better protection against airborne infectious diseases. This device can reduce particulate matter up to 94% in five minutes, directing quality air to the users.
Contact Our Experts for Custom Environmental Control Systems
MyZone® personal climate control systems provide a more comfortable, energy-efficient, and safe environment for employees. It offers unmatched flexibility, versatility, control, comfort, and user safety to maximize productivity and optimize the workplace environment.
Deciding how and where to best care for senior citizens as they get older can be an emotionally fraught experience. There are also several practical considerations that go into the decision to ensure their needs are met. Whether families decide to move their elderly parents in with them or to keep seniors in their own homes, a top priority is facilitating both a safe and healthy environment.
The National Institute on Aging advises people aging in place to install grab bars, ramps, and non-slip adhesives in their homes. Access to nutritious meals and following strict medication regimens are also advised. Experts recommend regular handwashing to prevent infections, and the CDC strongly urges senior citizens to get vaccinated against both COVID-19 and influenza.
But there is even more that can be done to ensure high-quality air and infection control in a private residential setting. Here is what you need to know:
What Residential HVAC Systems Were Designed To Do
Residential HVAC systems are designed to ventilate and filter air to maintain adequate air quality and control temperature. Ventilation and filtration remove odors and trap dust, smoke, and pollen. However, residential HVAC systems are not designed to capture toxic microorganisms.
HEPA filters capture pathogens which include bacteria, viruses, and even mold spores. Unlike hospital-grade HVAC systems, most residential units do not generate powerful enough airflow to overcome resistance caused by HEPA filters. Therefore, adding one to a home HVAC system is not a viable means of containing contaminants.
One way to reap the benefits of HEPA filtration in homes is through air purifiers equipped with HEPA filters. Since they reduce the number of particles that carry viruses by approximately 95%, they are considered medical grade.
Humidity Control Matters, Too
According to the International Journal of Environmental Research and Public Health relative humidity (RH) levels between 40-60% are optimal in homes for two reasons. First, mucous membranes are most resistant to infection around moderate humidity levels. Second, viruses living in aerosol particles survive for less time at 50% RH than in drier or very humid conditions.
Humidity control is not standard in residential HVAC systems, but it can be added retroactively. However, humidity control functionality that is incorporated into furnaces or central air conditioning only works when the system is running. Similarly, controlling humidity levels is not available through forced-water heating that uses boilers. If moisture control is not available through a household HVAC system, a stand-alone humidifier that monitors room levels will get the job done.
Volatile Organic Compounds
Exposure to volatile organic compounds (VOCs) can have short- and long-term adverse health implications. VOCs are gases emitted from various household products including new carpets, aerosol sprays, paint, PVC plastics, and air fresheners. VOCs originate indoors, and exposure to moderate levels of VOCs over time or high levels of VOCs in a short period of time can cause minor eye, nose, and throat irritation. Over time, higher concentrations of VOCs can cause liver, kidney, and central nervous system damage.
Air Purifiers Have Their Limits
According to Consumer Reports, air purifiers can remove contaminants only when they are floating in the air. Mites, mold, pollen, and VOCs are too heavy for most air purifiers. Units with HEPA filtration can capture aerosol droplets on which the coronavirus travels, but not all purifiers draw in enough air to actually reduce the volume of particles.
The Bottom Line
Avoiding harmful contaminants and facilitating quality indoor air is achievable, even in a private setting. Fortunately, a highly effective solution can be as simple and unobtrusive as a window AC unit.
Air Innovations brought over 25 years of experience designing and manufacturing customized solutions for temperature, humidity, and filtration control to its HEPAiRx® window-mount ventilating air purifier. The HEPAiRx system is a plug-and-play air filtration device comparable in size to a standard AC unit. The system quickly and thoroughly purifies a room of airborne particles and contaminants because each unit features medical-grade HEPA filtration and ventilation to exhaust air for a standard-sized room every 30 minutes.
The HEPAiRx unit brings in a high enough quantity of fresh air to naturally dilute VOCs without requiring a window to be open. It also uses upstream UV-C to kill viruses trapped on the intake side of the HEPA filter to give seniors an extra buffer against life-threatening elements. Lastly, the system has onboard heating, cooling, and humidity control features to keep residents comfortable.
The HEPAiRx system is currently the only solution on the market that can do the following:
Brings dedicated fresh air into a room to naturally dilute potentially harmful aerosol particles, VOCs, and gases.
Uses optional upstream UV-C to kill viruses trapped on the intake side of the HEPA filter – the only effective way to kill viruses on the HEPA filter.
Integrates the HVAC to isolate the space from the existing systems. HVAC ductwork is a source of cross-contamination between spaces. The HEPAiRx system seals off the current system to separate it from adjacent rooms creating an actual isolation space.
Air Innovations’ HEPAirX system empowers adult children to take a proactive approach to keep beloved older family members safe and healthy. Or, the unit enables senior citizens to take charge of their own contamination control.
The global pandemic exposed a need to elevate the standard of care for the elderly. In particular, senior citizens living and spending time in group settings such as nursing homes, residential care facilities, and senior centers were at exceptionally high risk for contracting and dying of COVID-19.
As of April 2021, the U.S. Department of Energy reported that residents in long-term care facilities accounted for only 3% of the total 21 million confirmed COVID-19 cases in the U.S., yet made up one-third of the 350,000 deaths. Nursing home residents are particularly susceptible to COVID, and other infections, due to their naturally lowered immune functions and being prone to pre-existing conditions. Additionally, nursing homes lack the systems engineered to control the spread of potentially life-threatening contagious diseases, like COVID.
Various tactics are needed to prevent the spread of infections where older adults live and congregate. Fortunately, armed with some vital information, facilities can take steps to protect their communities better.
The Role of Ventilation And Filtration
Similar to other contagious pathogens, it became evident that COVID spreads primarily indoors. Beyond physical distancing and masking, the best way to reduce the spread is by implementing air ventilation and filtration systems.
According to the Journal of the American Medical Association (JAMA), “The weight of evidence indicates ventilation plays a key role in infectious disease transmission, (…) showing low ventilation associated with transmission of measles, tuberculosis, rhinovirus, influenza, and SARS-CoV-1.”
Elevate Ventilation Standards
Yet, JAMA also reports that most indoor spaces (except for hospitals) ventilate and filter air at minimum levels.
The American Society of Heating, Refrigeration, and Air Conditioning Engineers (ASHRAE) sets ventilation standards for most indoor spaces. However, these standards are intended to remove odors and ensure an adequate level of air quality. They don’t support an infection control strategy.
Better Filtration Plays A Key Role
Air filters and purifiers have several efficiency standards, including clean air delivery rate (CADR) and minimum efficiency reporting value (MERV). Established by ASHRAE, the MERV rating measures the quality of air filters used in central ventilation systems. For reference, MERV-8 is a typical low-grade filter that captures only 15% of small particles. MERV-13 filters are able to capture nearly 70% of small air particles and are an integral part of a larger infection control program. Standards for nursing home resident rooms require only MERV-7 filters.
HEPA filters are used in any application that requires contamination control. Air purifiers equipped with HEPA filters can capture even smaller microns than MERV filters. Since they reduce the number of particles that carry viruses by approximately 95%, they are considered medical grade.
Upgrading filters to capture a higher percentage of particles of all sizes is a reasonably simple way to protect the elderly living in long-term care facilities.
Incorporate Fresh Air
Researchers have found that fresh air delivered through AC or ventilation systems plays an important role in diluting the volume of viral aerosol particles in a room. Monitoring carbon dioxide (CO₂) levels is a simple way to ensure enough fresh air is in a room, as high CO₂ levels indicate that there is a lot of exhaled air in the room. A sick person has a greater chance of distributing viral particles to a healthy person.
Relative Humidity Matters, Too
In addition to regular ventilation and air filtration, the International Journal of Environmental Research and Public Health recommends maintaining relative humidity (RH) levels between 40-60% for two reasons. First, mucous membranes are most resistant to infection in moderate humidity levels. Second, aerosol particles potentially containing contagious diseases can live for less time at 50% RH than in drier or very humid conditions.
Facilities and residences for older people can monitor humidity and utilize humidifiers as needed at a low cost.
The Bottom Line
A multi-pronged approach is the best way to protect older citizens from low-quality air and infectious diseases. Fortunately, a highly effective solution can be as simple and unobtrusive as a window AC unit.
Air Innovations brought over 25 years of experience designing and manufacturing customized solutions for temperature, humidity, and filtration control to its HEPAiRx® ventilating and filtrating system. HEPAiRx systems are air filtration devices that are comparable in size to a standard AC unit. They combine multiple strategies for maintaining optimal health in a variety of applications. HEPAiRx units quickly and thoroughly purify a room of airborne particles and contaminants. Each plug-and-play unit features a MERV-17 medical-grade HEPA filter and ventilation to exhaust air for a standard-sized room every 30 minutes.
HEPAiRx systems are an ideal solution for use in nursing homes. Since each unit is entirely self-contained and compact, facilities don’t have to overhaul their existing HVAC systems. HEPAirX units empower facility administrators to take a proactive approach to keep our beloved older family members and staff safe and healthy.
The HEPAiRx system is currently the only solution on the market that can do the following:
Bring dedicated fresh air into a room to naturally dilute potentially harmful aerosol particles, VOCs, and gases.
Create either a negative or positive pressure environment.
Use optional upstream UV-C to kill viruses trapped on the intake side of the HEPA filter – the only effective way to kill viruses on the HEPA filter.
Integrate the HVAC to isolate the space from the existing systems. HVAC ductwork is a source of cross-contamination between operatories. When using the HEPAiRx system, you can seal off the existing system to separate it from adjacent rooms, creating an actual isolation space.
COVID-19 has put healthcare facilities under extraordinary pressure to accomplish more with less. Nurses and doctors had to care for waves of sick patients with limited resources. Medical personnel simply didn’t have the equipment or facilities needed to keep up with patient demand, and they struggled to contain the virus with makeshift solutions.
The most obvious way to protect patients and staff from those infected with COVID-19, or any other infectious disease, is to isolate them. Proper isolation rooms have dedicated HVAC and HEPA filtration capabilities. These rooms are constructed according to stringent guidelines from the CDC and other professional associations. Isolation rooms don’t share air or controls with the rest of the medical facility to prevent the risk of cross-contamination. However, at the height of the pandemic, even the most advanced, well-funded institutions could not isolate their contagious patients.
Protecting Patients and Staff
The most common type of isolation room utilizes negative pressure. These spaces have lower pressure inside the room than in the surrounding environment. As a result, contaminants can’t sneak out of the room and spread to the rest of the hospital. A negative pressure environment is maintained by using a dedicated HVAC system that continuously pumps clean air into the room near the floor and filters and sucks it back out through a grill near the ceiling. Other patients and medical staff are protected from the sick person.
Positive pressure rooms maintain higher pressure inside a space than the surrounding environment. These rooms are connected to a hospital HVAC system, which pumps clean, filtered air into the room. When the door to the space is opened, the high pressure forces out clean air and prevents any contaminants from entering the area. Positive pressure rooms are valuable for compromised patients—burn victims, surgery patients, birthing women, and injured emergency room patients—highly susceptible to infection or pathogens.
Perhaps now more than ever, building isolation spaces dedicated to protecting and treating vulnerable patients is a prohibitively expensive option for most hospitals.
Between forced facilities shutdowns and increased costs surrounding COVID-19 preparedness, U.S. hospitals lost an estimated $323 billion in 2020. Moreover, hospitals and health systems are projected to lose between $53 to $122 billion more in 2021. Beyond shrinking budgets, administrators can be slow to adopt change due to protracted stakeholder approval processes. The path of least resistance is often to maintain the status quo.
Versatility for Enhanced Level of Patient Care
Air Innovations strives to truly understand the challenges our customers and potential clients grapple with beyond controlling temperature and humidity. Adopting a holistic approach enables us to engineer lasting solutions that are adaptable to meet their evolving needs.
We designed the IsolationAir® system so that hospitals and medical facilities could continue delivering high-quality care to their most vulnerable patients without taking on a renovation project. Our systems convert standard-sized patient rooms into positive or negative pressure spaces depending on demand. Since the unit is portable, it limits the need for stakeholder approval often required for renovation projects. IsolationAir contamination control units are considered devices and not intrinsic parts of a hospital.
HEPA Filtration & UV Light
The portable unit includes medical-grade HEPA filtration to remove potentially harmful particles from a negative pressure space or into a positive pressure patient room. The unit also has UV-C light to sterilize contaminants that stick to the back of the unit and can be ingested by sick patients.
Designed for Patient Comfort
IsolationAir systems have onboard heating and cooling to keep patients comfortable when they are cut off from the hospital HVAC system. The AC functionality also serves to dehumidify exam and patient rooms.
Each unit comes equipped with flexible ductwork, and there are two ways to implement them.
To boost readiness to respond to increased patient volumes, hospitals can pre-facilitate inpatient or exam rooms by having a universal grill adapter connected to the return grill in the ceiling. At that time, maintenance staff can check for other air exhausts or leaks in the room and seal them up. When it becomes necessary to expand surge capacity for any reason, hospital staff can rapidly deploy an IsolationAir unit by simply plugging the unit into an emergency outlet and connecting the flexible ductwork to the available adapter.
Alternatively, medical facilities can simply wheel an IsolationAir unit into a particular exam or treatment room and install a return grill adapter to which the flexible ductwork on the unit will connect. Maintenance teams can seal up visible air leaks around windows and doors. Once on-site, the process takes less than an hour and doesn’t require specialty HVAC professionals. Installing a return grill adapter as needed before connecting the unit’s ductwork is a viable option when hospitals can foresee a rise in patient demand, as we did with COVID-19.
When Flexibility Matters Most
Anytime a room is used to “open up” patients, they are immediately susceptible to potentially life-threatening pathogens. Dedicated surgical theaters are typically designed as positive pressure rooms. However, there have been instances where hospitals have opted to permanently convert surgical spaces from positive rooms to negative rooms, a transition that requires planning and time.
Trauma patients and burn victims have the best chance of survival when treated in positive pressure rooms. Issues arise when a crisis happens, and hospitals don’t have enough positive pressure rooms to treat victims. The flexibility to transform an unpressurized room into a positive pressure space quickly enables a medical establishment to treat and save more patients.
Surprisingly enough, most labor and delivery floors and emergency units don’t have contamination control even though these patients are vulnerable to infections. Often, it is impossible to anticipate whether rooms should be positive or negative pressured spaces. Hospitals, extended care facilities, and emergency preparedness centers need the flexibility to determine—sometimes on the fly—whether patients need positive or negative pressure to save their lives or to prevent catastrophe.
The Final Verdict
Despite the enormous challenges and constraints facing hospitals today, administrators have solutions available to help them respond with agility to varying patient needs. We are proud our IsolationAir system can help medical professionals do their jobs easier and enable them to save more lives. When it comes to creating spaces to care for our most vulnerable patients, versatility is the name of the game.
IsolationAir® Systems meet the following industry guidelines:
12 air changes per hour via HEPA filters
Each IsolationAir unit conditions rooms up to 375 sq ft with an 8’ ceiling
A pressure differential of 0.01” minimum between a room and adjoining spaces (May require additional seals around doors or other significant leak points in large rooms with poorly sealed doors).
Continuous operation when plugged into an emergency generator outlet
Provides stable temperature control for patient comfort
Originally designed to meet the U.S. Department of Health and Human Services’ critical benchmarks:
Negative or positive pressure rooms are often necessary to prevent contamination and maintain a climate-controlled environment in various applications. While these rooms are somewhat similar, there are certain differences between their designs and requirements. Here we’ll give an overview of both of these types of environments, including their intended applications and design requirements.
Negative Pressure Rooms
Negative pressure rooms have air pressure that is lower than the external air pressure. Negative pressure is achieved through the use of an exhaust system that frequently includes a high-efficiency particulate air (HEPA) filter connected to a sealed room. These rooms can trap potentially dangerous particles to prevent cross-contamination in external air. This is why they’re often used to isolate infected patients while keeping people outside of the room consistently safe.
Negative pressure rooms are designed to contain airborne infections. To do so, there are various design requirements that these rooms must follow, which are outlined by CDC Guidelines, ASHRAE standards, and Healthcare Design Construction Guidelines. As summarized in these guidelines:
Negative pressure rooms must undergo at least 12 total room air changes every hour.
They need to maintain a negative pressure differential of at least 0.01’’.
Exhaust from these rooms and any connected anterooms or toilet rooms needs to travel directly outdoors with no chance of contaminating exhaust from other spaces.
If an anteroom is included in the setup, airflow needs to travel into the anteroom via the corridor. From there, it should be channeled into the patient isolation room.
The quantity of air exhaust needs to be higher than the supply airflow to maintain a consistent pressure differential.
The exhaust grille must be located in the ceiling and near the head of the bed.
All exhaust air must be discharged through a HEPA filter if the fan is below the roof line.
Misconceptions About Negative Pressure Rooms
One potentially dangerous misconception about negative pressure rooms is that medical personnel are safer when performing aerosol-generating procedures on patients in these rooms. This is due to the Centers for Disease Control and Prevention (CDC) recommendation that these procedures be performed in isolation rooms. However, negative pressure rooms do little to protect individuals inside the room. Their main purpose is to help protect people outside of the room by keeping aerosols and other particles within the room.
Positive Pressure Rooms
A positive pressure room is intended to protect patients from infectious diseases if they’re immunocompromised. While this type of room is somewhat similar in concept to negative pressure rooms, it features certain differences in its function and design. Positive pressure rooms contain a higher pressure in the containment area than the external environment, preventing air from leaving the room and circulating back inside. This prevents occupants in the room from being exposed to any outside contaminants, including potentially harmful particles and germs.
Positive pressure rooms must follow various design requirements to keep patients protected from outside contaminants. Included in these requirements are the following elements:
Positive pressure rooms require at least 12 air changes every hour.
They must maintain a minimum positive pressure differential of 0.01’’.
If anterooms are used, the airflow must travel to the anteroom from the patient room and then into the adjacent corridor.
Normally, a 150 to 200 CFM airflow difference is sufficient for maintaining the ideal pressure differential in these rooms.
HEPA filters are required to supply clean air. These filters are normally located at the room’s supply terminals or the main air-handling unit.
Airflow to the room needs to stay at a constant volume for consistent ventilation.
Create Custom Positive and Negative Pressure Environments with Air Innovations
If you require flexible positive or negative pressure rooms for your application, Air Innovations has the expertise and solutions you need. Our IsolationAir® unit offers a portable contamination control system that can efficiently convert standard-sized patient rooms into either positive or negative pressure environments. Some of the features of our IsolationAir® system include ductwork, UV sterilization, and HEPA filtration connections. The system also allows for temperature control, isolating the room from the central HVAC system.
Learn how Community Health Net created Negative & Positive Pressure Environments to create better patient outcomes and safer spaces for employees and patients. Watch the video below.
For more information about our systems, contact us today. You can also request a quote to get started on a custom solution for your project.
Negative pressure rooms control airborne pathogens by exhausting contaminated air from the building while preventing the air from leaking into other parts of the facility. These rooms are a necessity to maintain the safety of guests, patients, and hospital staff.
At Air Innovations, Inc., our expertise in negative pressure HVAC systems will ensure that your hospital’s negative pressure rooms comply with industry standards.
What Are Negative Pressure Rooms?
Negative pressure rooms have inside air pressure that is lower than the air pressure outside of the room. This serves to prevent contaminated air from exiting the room while allowing non-contaminated air to flow into it. Contaminated air flows through a controlled HVAC system, where the air is purified using specialized filters before it exhausts from the facility.
Creating Negative Air Pressure in a Hospital Room
Negative pressure rooms are crucial in hospital settings as they isolate airborne diseases like COVID-19, SARS, and MERS from the rest of the facility and prevent them from spreading to patients, staff, and guests. A negative pressure room requires a dedicated space, where a barrier will keep the room as air-tight as possible. For isolation rooms in more open areas, a heavy plastic curtain can block air circulation. If the area has a door, it is important to block any gaps to create a tight seal.
When establishing an isolation room in a hospital, the HVAC system will require adjustments to ensure the room has a continuous inflow of fresh air. The contaminated air must be forced out through exhaust vents with a filtration system to purify the air before it exits the facility. An existing HVAC system may be suitable, or a portable contamination system can be used to focus on a particular area.
Types of Negative Pressure Isolation Rooms
There are two classes of negative pressure isolation rooms, class N and class Q. A class N room isolates airborne diseases within a room to protect the facility from exposure. They are typically near the entrance of an inpatient ward to prevent the spread of the disease during patient transport.
Class Q rooms also isolate airborne diseases but implement stricter safeguards. Some primary features include an anteroom, self-closing doors, a private restroom to keep the isolation room sealed, and a ventilation system that prevents exhausted air from re-entering the isolation room. Class Q rooms also feature a monitoring system that alerts staff if the pressure changes. These are all crucial features to ensure optimal infection control.
Hospital Spaces to Negatively Pressurize
Various hospital spaces should be negatively pressurized for safety and compliance. According to ANSI/ASHE/ASHRAE standard 170-2017 of the 2018 FGI guidelines, negative pressure spaces include but are not limited to:
Isolation Rooms for Airborne Infections
Public Waiting Areas and Radiology Department Waiting Areas
Emergency Department Decontamination Bays
Various Laboratory Work Areas
Sterile Processing Areas and Soiled Decontamination Areas
Soiled Workrooms and Holding Rooms
Soiled Linen Sorting and Storage Areas
General patient examination, X-ray, and nursery areas typically do not require negative pressure rooms.
Testing and Monitoring Room Pressure
Monitoring for consistent low pressure in an isolation room is vital to ensure the safety of a facility. While a tissue or smoke capsule can confirm if the room is pressurized, modern equipment provides continuous monitoring of the room’s pressure. Electronic monitoring devices can be placed inside the isolation room and outside to trigger an alarm when the pressure reaches a set threshold. Regular inspection is necessary to ensure the devices are not contaminated or broken.
Contact the Experts at Air Innovations for Custom HVAC Systems
Air Innovations offers specialty environment control units to meet the needs of various critical applications. Our IsolationAir® portable contamination systems deploy quickly to isolate a sterile environment and prevent cross-contamination. These systems come equipped with UV sterilization, HEPA filtration, and ductwork connections. Whether you need to turn a room into a negative or positive pressure environment, our IsolationAir® system offers the ideal solution.
Our expertise will ensure your isolation rooms are compliant with ASHRAE, AIA, and CDC guidelines to protect patients, staff, and guests. Contact us to speak with a representative or request a quote to learn more.
At Air Innovations, we’ve designed, manufactured, and tested custom environmental control solutions for OEMs and non-OEMs for over 30 years. This extensive experience provides us with the knowledge and skills needed to deliver appropriate systems for a wide range of industries. One of the key markets we serve is the healthcare industry. Healthcare professionals know they can rely on us for products that keep their patients and personnel safe and healthy, such as hospital isolation room systems.
Below, we provide an overview of hospital isolation rooms, outlining the types available and key considerations to keep in mind when building one for a healthcare facility. Additionally, we highlight the products we offer that can be used to help build isolation rooms.
WHAT ARE HOSPITAL ISOLATION ROOMS?
In hospitals and other healthcare facilities, controlling the spread of infectious diseases is critical to keeping patients, personnel, and visitors safe and healthy. An important element of a comprehensive infection control strategy is the use of isolation rooms. These specialized rooms are designed to decrease the likelihood of cross-infection among people within the facility by controlling the flow of air within the room to reduce airborne infectious particle levels. They can achieve this goal in a number of ways, including by controlling the quantity and quality of intake or exhaust air, maintaining an air pressure differential between adjoining areas, directing airflow in a specific pattern, diluting room air with large volumes of clean air, and cleaning the air with high-efficiency particulate air (HEPA) filters.
TYPES OF HOSPITAL ISOLATION ROOMS
Isolation facilities can be configured in several ways, including the following:
Standard Rooms. These rooms utilize standard room (neutral) air pressure levels. They have normal HVAC systems and may or may not have a clinical handwash sink, en suite shower and toilet facilities, and a self-closing door. While they are generally used for patient contact isolation applications, they can be used for normal patient care when isolation is not required.
Airborne Infection Isolation (AII) Rooms. These rooms—also referred to as infectious isolation rooms—utilize a negative-pressure differential. They have lower pressure levels than adjacent rooms so air will rush inward rather than outward when the room is opened. This design prevents airborne infectious particles from escaping into other areas of the healthcare facility. They are employed as single-occupancy rooms to isolate patients with suspected or confirmed airborne-transmissible infections.
Protective Environment (PE) Rooms. These rooms utilize a positive-pressure differential. They have higher pressure levels than adjacent rooms so air will rush outward rather than inward when the room is opened. This design prevents airborne infectious particles from entering the room from other areas of the facility. They are utilized to protect immune-compromised patients from airborne-transmissible infections.
KEY CONSIDERATIONS WHEN BUILDING AN ISOLATION ROOM
Due to their critical function, isolation rooms must be designed and constructed carefully. Otherwise, there is an increased risk of cross-contamination between patients, personnel, and visitors. While there are many factors to consider to ensure an isolation room will work properly, some of the key ones include air changes per hour, HVAC, pressure control, temperature control, and supplemental controls.
AIR CHANGES PER HOUR (ACH)
As per the infectious disease control guidelines outlined by the Centers for Disease Control (CDC), isolation rooms should have a minimum of 12 air changes per hour using medical-grade HEPA filters. These filtration units are designed to remove 99.97% of airborne particles that are ≥0.3 µm in diameter. The American Institute of Architects (AIA) further specifies that a minimum of 12 air changes per hour are required for new facility constructions and renovations, while a minimum of six air changes per hour are required for existing facilities.
HVAC systems play a vital role in hospitals and other healthcare facilities. In addition to regulating airflow and maintaining comfortable temperature levels, they also help minimize the transmission of airborne diseases. When properly implemented, they can prevent the spread of contaminant-laden air through air purification, improved ventilation, and airflow control.
Standard rooms do not require a specialized HVAC system.
Negative pressure rooms require dedicated supply and exhaust systems separate from the building’s systems that do not permit any return air. A HEPA filtration should be connected to the supply system if the room will be used for isolating immunosuppressed patients. Additionally, the air conditioning system should be connected to an emergency power supply to prevent depressurization in the event of power loss.
Positive pressure rooms can share an air system with the building as long as the minimum outdoor air requirements meet local requirements and restrictions. However, the supply air inlet should be fitted with a HEPA filter.
The recommended minimum differential pressure between the isolation room and adjacent rooms is 2.5 Pa (0.01” water gauge) for both negative and positive rooms.
Isolation rooms must be appropriately heated or cooled to maintain an average temperature of 75°F.
Ultraviolet germicidal irradiation can be used as a supplemental air-purifying measure.
ACHIEVING CONTAMINATION CONTROL WITH AIR INNOVATIONS
We offer a broad selection of products that help control contamination in healthcare facilities. For example, our IsolationAir® portable contamination systems can be used to turn standard-sized rooms into negative-pressure or positive-pressure isolation areas for patient care or containment in as little as 30 minutes. They quickly and easily create a sterile environment in an isolated space that prevents cross-contamination, ensuring patients and personnel are better protected against infectious diseases. IsolationAir systems have several key features:
American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)
Download our IsolationAir brochure for more details about our line of standard hospital contamination control systems.
CONTACT US FOR YOUR ISOLATION ROOM ENVIRONMENTAL CONTROL NEEDS
In medical facilities, dedicated isolation rooms are a critical tool for controlling airborne disease transmission. These spaces can be expensive to build and often require extensive airflow control measures to prevent cross-contamination with the rest of the facility effectively.
At Air Innovations, we understand the importance of airborne disease control in the healthcare industry. Our CDC, AIA, and ASHRAE-compliant IsolationAir® contamination control systems help hospitals, extended care facilities, and emergency preparedness centers improve their surge response capabilities and infectious disease preparedness. The portable units can be quickly and conveniently deployed to convert standard rooms into isolated environments for a number of applications, saving healthcare facilities time and money.
To learn more about our environmental control solutions and how they can benefit healthcare facilities, contact us today.
All heating and cooling air duct systems naturally collect dust and contaminants. Clean rooms, such as those used in the electronics, pharmaceutical, and medical industries, require a controlled environment free of dust, airborne particles, and other contaminants. Ultra low particulate air (ULPA) filters and high efficiency particulate air (HEPA) filters are used in commercial air filtration systems to trap extremely small particulate contaminants.
ULPA vs. HEPA Filter
ULPA and HEPA filters share many characteristics but differ in some crucial aspects. Both filters use layers of dense fibers to create a fine mesh filter that removes contaminants as air is forced through them. Both HEPA and ULPA filters use a combination of three main methods to trap contaminants: diffusion, interception, and inertial impaction.
ULPA filters trap more and smaller particulate matter than HEPA filters. ULPA filters are 99.999% effective at removing submicron particulate matter of 0.12-micron diameter or larger, while HEPA filters are 99.97% effective for eliminating particulate matter of 0.3-micron diameter or larger. HEPA filters can be combined with pre filters to trap larger particles before they come into contact with the main filter.
The higher efficiency rating of the ULPA filter is due to the increased density of the filter medium, which allows airflow up to 50% lower than HEPA filters and requires more power to move air. HEPA filters have a lifespanofup to ten years, whereas the typical life cycle of an ULPA filter ranges from five to eight years. Choosing the right filter for your application depends on containment regulations and standards in your facility.
Which Air Filter is Better – ULPA or HEPA?
Filter manufacturers often stress the superior efficiency rating of ULPA filters when compared to HEPA filters. While ULPA filters trap more and smaller particulates, they are usually less effective at reducing the overall particulate concentration in a typical room than the same air filtration system equipped with HEPA filters. This is due to reduced airflow caused by the dense filter material of ULPA filters. ULPA filters typically pass 20-50% less air than HEPA filters, which results in the room having fewer air changes per hour.
There are a variety of HEPA filters available, some of which are more complex than others. These complex HEPA filters exceed the typical MERV scale of rating, making them the most effective and popular option for many industries.
Choosing the Best Air Filter for Your Application
Determining the best filter for your application requires a careful analysis of your needs and any containment regulations for your facility, including the minimum number of air changes required per hour. HEPA and ULPA filters are designed for use in a variety of applications, including industrial vacuum cleaners to remove asbestos, removing toner dust from office equipment, preventing the spread of airborne bacteria in surgical operating rooms, and other crucial medical air filtration applications.
Industries such as pharmaceutical, photography, electronics, and more all rely on air filtration systems to protect their equipment and keep people safe. Understanding the requirements of your application and the level of effectiveness needed will help you choose the right air filter for your needs.
Air Filtration Solutions from Air Innovations
At Air Innovations, we are experts at designing and building air filtration systems for applications that are difficult to address with standard HVAC equipment. We specialize in creating custom solutions that meet containment regulations and any other standards required for your application. Our mission is to design and build an air filtration system that you can rely on to meet the precise tolerances and parameters you need. To request a quote for your application or to learn more about our air filtration systems, contact us today.
There are a handful of professions serving mission-critical functions wherein personal comfort plays a vital role in productivity. From command centers to 911 call centers, having control over heating and air conditioning, as well as desk-lift functions, can make a difference when it matters most. In addition to providing control over environmental factors, Air Innovations has also prioritized making the functionality of the desktop management system as efficient and customizable as possible.
What Do We Mean By Micro Environment?
One person might feel most energized at a standing desk in a brisk 65℉ room. Another professional sharing the same office might focus best sitting down in a warmer space. Ensuring comfort is necessary when attention to detail and quick decision making is critical to the job function. At Air Innovations, a “Micro Environment” is a desktop management control system that delivers this level of custom comfort.
At the heart of a Micro Environment system is the ability to control the temperature around a desk. Users can adjust the speed of the cooling fan and regulate the output of the forced air heating. In addition, our Micro Environment units enable users to adjust the louvers to direct air to their liking.
Moreover, the air circulating around the desk first passes through a filter that can trap airborne contaminants such as dust mites, carpet fibers, and mold spores.
Air Innovations’ Micro Environments systems were designed with efficiency in mind. The goal is to provide professionals with everything they might need—at their fingertips—to maximize productivity.
Controlling the functions of a Micro Environment unit, including climate, lighting, and integrated desk-leg lift, which starts with a color touch screen. The consoles include a USB charger, light, and auxiliary power source to plug in a mobile phone charger or radio reducing the need to rummage around for cords and outlets. The digital control console is compatible with any type of office desk.
Users may also take advantage of the motion sensor that is triggered after 10 minutes of no activity, which turns off any lights and deactivates the fan and heat. Once the person returns, the system activates and returns the fan, heater and task light to the last setting.
The controls box is made of a commercial-grade powder-coated, lightweight aluminum, taking up a small footprint on any office desks. One added benefit is that all of these accessories require the lowest power usage of any Micro Environment on the market.
Efficiency is one thing; being able to customize one’s office environment is what takes personal comfort and productivity to a new level. With our solutions, customization begins at installation.
The controller is not fixed to the console so the user is able to place it either above or below the desk. The lighting is dimmable to provide professionals with options depending upon the time of day or their particular needs at any given moment. The desk-leg lifts can be adjusted to several sitting or standing levels to accommodate user preferences and heights.
The ability to customize the main screen with a personal picture, eliminate or add apps, a memory function for multiple users, field upgradable software, a white noise machine and auxiliary input jack are additional features that round out the Air Innovations micro environment systems.